This section brings you the most frequently asked questions and a lot of answers related to TRISOMY test.

What sorts of things is TRISOMYtest capable of detecting? How reliable is it?

TRISOMY test is designed to exclude the presence of foetal trisomy associated with chromosomes 21, 18 and 13, which correspond to Down, Patau, and Edwards syndromes, respectively. The test has a sensitivity of more than 99%. It is a non-invasive, safe and painless screening method based on a sample of maternal blood and it can be carried out as early as in the 11th week of pregnancy. If the mother-to-be wishes to know, the test can also reveal the sex of her unborn baby. For more information, click here.

I’d like to know more about TRISOMY test. How and where does the procedure take place?

If you want to get screened, contact a gynaecologist or a clinical geneticist anywhere in Slovakia. After a short consultation with your doctor, a female nurse will take a sample of your blood and send it to the Central Laboratories of Medirex a.s. in Bratislava, where blood samples are processed and analysed. Click here to read more about the whole procedure.

Which week of pregnancy is the last possible week I can get screened in?

TRISOMYtest screening is most frequently carried out between the 11th and 22nd week of pregnancy. Whether the mother-to-be chooses to get screened in the earliest or the latest stage possible is a matter of her preference and her doctor’s recommendation based on her health condition. Click here for more information.

I’ve decided to have a TRISOMYtest done. Do I have to give a blood sample on an empty stomach?

No, blood samples need not be taken on an empty stomach. Click here for more information.

I’d like to have a TRISOMYtest done but my doctor says he/she is not affiliated with your company. Is it also possible to have a blood sample taken at your facility or another doctor’s surgery?

It is not possible to have a blood sample taken at our laboratory. You can only get screened provided that you have been referred for the test by your doctor, i.e. either your usual gynaecologist or a clinical geneticist. To request a screening, contact one of the medical specialists listed on our website. The list can be found in the section entitled “Where to get tested”.

Do I need a medical referral from a gynaecologist to have a TRISOMYtest done?

Yes, you can only be referred for the test by a gynaecologist or a geneticist, who will also take a sample of your blood. As they are perfectly familiar with your medical history, your doctor is the best person to interpret your test results.

How soon can I expect my test results? Your website says TRISOMYtest results are delivered within 5 working days of payment but I’m not sure if the days of blood sampling and making the required payment are actually included in the period.

Our laboratory sends your TRISOMYtest results to the doctor who referred you for the test, typically within 5 working days from the day your payment is credited to the laboratory account. If you make the required payment on the day of blood sampling, the day may be included in the period, although this usually depends on the speed of the communication between your bank and our laboratory’s bank. As soon as we identify your payment in our account, we begin analysing your sample, which usually takes up to five working days.

When I was filling in the order form at my doctor’s surgery, I requested to be notified of my test results by phone. I’ve tried phoning your laboratory but they refused to give me the results over the phone. Why?

The order form that you and your doctor filled in at the time of blood sampling is designed for two different tests – TRISOMYtest and BabyGen. The option of receiving test results by phone or email only applies to BabyGen,  which is designed to detect the sex of your unborn baby. In contrast, the results of TRISOMYtest screening contain sensitive information concerning your health condition. In the circumstances, the laboratory acts in accordance with current legislation and does not send any information directly to patients as laboratory test results might indicate health-related complications. Instead, test results are delivered directly to your doctor, who is perfectly familiar with your health condition. If necessary, they can recommend additional steps with regard to both yours and your baby’s health. This procedure (delivering test results via your doctor) remains the same no matter whether your TRISOMYtest results are positive or negative. Click here to read more about the whole procedure.

Can I pick up my TRISOMYtest results from the laboratory?

As a rule, although test results are produced directly in our laboratory, the only person who can interpret the results to you is your doctor. Respecting the role of your doctor in the process of providing health care services, the laboratory does not provide test results directly to patients. As a rule, TRISOMYtest results are delivered to your doctor electronically, subsequently also in written form.

I received a text message that says my blood sample had been successfully analysed. Today is the 6th day since the day my blood sample was delivered to you, the day I made the required payment for the test. Although I explicitly requested in the TRISOMY test order form that my test results be sent to my email address, I have not received any information regarding my test results so far.

As soon as the analysis of your blood sample is finished, we will send you a text message to confirm that your blood sample has been successfully analysed. Instead of sending results directly to the patient, however, we inform the doctor who referred them for the test. Please, contact your doctor to find out about the results of the analysis. Your doctor is perfectly familiar with your health condition. If necessary, they can recommend additional steps with regard to both yours and your baby’s health. Click here to read more about the whole procedure.

Is it possible that the results of my TRISOMYtest screening might not be delivered to my doctor in time? How likely is it that they will be delayed?

Delays are likely to occur when the screening process or a part of the analysis must be repeated – mostly due to biological variation in the composition of blood samples. Although it is rare, such variation is natural. However, blood samples have to be analysed again in a very small percentage of all cases, usually less than 5%. Under normal circumstances, the analysis of blood samples is completed within 5 working days.

Is it possible to post a blood sample to your laboratory to have it analysed? We are living abroad at the moment. 

Yes. Our laboratory staff analyse blood samples as long as they are sent by air mail. In the circumstances, however, a special test tube and a special order form are required, which can be sent to your temporary address on request. Your gynaecologist must fill in the required order form (in English), providing details of your anamnesis and specifying the gestational age of your baby. Blood samples must be taken by a female nurse so that they are not contaminated by male DNA, which might interfere with the process of determining the sex of your unborn baby. Make sure you take postage charges into account on top of the standard cost of our laboratory analysis.

Can TRISOMY test also detect developmental defects, such as spinal malformations?

No, TRISOMY test is not designed to detect schistorrhachis. It is only designed to exclude trisomy related to chromosomes 13, 18, and 21 and determine the sex of your foetus. For more information, click here.

Is it possible that Subcuvia injections for strengthening the immune system (human immunoglobulin) might distort my TRISOMY test results?

Human immunoglobulin cannot distort your results. Our screening is based on DNA analysis, and human immunoglobulin has no influence on your DNA.

Is it likely that screening may have to be repeated using a new blood sample for some reason?

Although repeated blood sampling and analysis are rare, you should be prepared for such circumstances given the complexity of the type of analysis involved. The most frequent reason for repeated TRISOMYtest screenings is a low proportion of circulating cell-free fetal DNA in maternal blood samples, which makes our analysis complicated. However, this naturally occurs only in about 5% of pregnant women. Samples containing a low proportion of fetal DNA make it impossible for us to arrive at a reliable diagnostic conclusion, which is why sampling and screening are repeated in the circumstances, typically about 10 days after the first blood sample was taken. Judging from our clinical experience, repeated samples are highly likely to lead to informative and diagnostically clear results. Should repeated sampling be necessary, we will contact both you and your doctor, suggesting you make another appointment with your doctor to have another blood sample taken. Repeated TRISOMYtest screenings are provided free of charge.

Is it possible that I might have to undergo amniocentesis after my TRISOMYtest screening?

Given the fact that TRISOMYtest is considered to be a screening method, all positive test results must be supported by genetic analysis based on amniotic fluid or chorionic villus sampling. If your TRISOMYtest results are negative, however, there is no need for you to undergo any invasive procedures. For more information, click here.

When I had a Triple screening test done, my results indicated a higher risk of Down syndrome. Where can I have a TRISOMYtest done?

TRISOMYtest is available all over Slovakia. Click here to see a list of doctors who offer this option. Since we keep updating it, the list of affiliated doctors on our website may not be complete. It is recommended that you ask your gynaecologist or a medical specialist in clinical genetics about the availability of TRISOMYtest screening in your particular region.

Is it possible that my TRISOMYtest results might be distorted by a previous blood transfusion? My TRISOMYtest results were negative, but I had previously received a blood transfusion. It was 24 years before, though. 

Blood transfusions are an important factor for us only if the patient received one in the 6 months or less prior to TRISOMYtest blood sampling. As for the long period you mentioned in your query, however, there is no need to worry about your recent test results being distorted at all.

Can the test provide relevant results when I’m expecting twins? Can it determine the sex of the individual babies?

Yes, the test can also be used in the event of multiple pregnancies, although there are a few limitations related to the type of examination that must be taken into account. TRISOMY test screening allows us tell that at least one of the unborn babies you are carrying is affected by a chromosome disorder the test is designed to detect. However, we cannot tell whether only one or both of your unborn babies are affected. As for the sex of your unborn babies, we can state that either both of your babies are female or at least one of them is male. Based on TRISOMY test screening, we cannot tell that one baby is male and the other is female or that both babies are male.